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Campylobacter Blog Surveillance & Analysis on Campylobacter News & Outbreaks

Campylobacter jejuni and Guillain Barre Syndrome

PharmaLive posted an update on the FDA’s watch on the Menactra (Meningococcal Conjugate Vaccine) and its connection to reports of Guillain Barre Syndrome. Although the article was about GBS as a result of vaccination, it is important to remember that Campylobacter jejuni and other gastrointestinal “bugs” can cause GBS in humans. From the article:

“Clinical data for other possible causes of GBS frequently were not available when investigating the 17 cases of GBS after MCV4 vaccination. Campylobacter jejuni is a leading cause of gastroenteritis and the most frequent antecedent pathogen in GBS cases (5). None of the patients had reported diarrheal prodromes; however, many C. jejuni infections are asymptomatic. Three of the 17 patients had stool cultures; one was tested for C. jejuni, and the results were negative. A serum sample from one of the patients was tested for C. jejuni, and the result was negative; no other serum samples were available for testing. None of the states where the patients resided reported outbreaks of C. jejuni during June 2005–September 2006.”